Structure-based drug design, synthesis and biological assays of P. falciparum Atg3-Atg8 protein-protein interaction inhibitors.
Stefania VillaLaura LegnaniDiego ColomboArianna GelainCarmen LammiDaniele BongiornoDenise P. IlboudoKellen E. McGeeJürgen BoschGiovanni GraziosoPublished in: J. Comput. Aided Mol. Des. (2018)
Keyphrases
- drug design
- protein protein interactions
- biological data
- high throughput
- biological processes
- protein protein
- protein interaction
- computational methods
- structural properties
- functional modules
- protein complexes
- essential proteins
- biomedical literature
- network topology
- protein structure prediction
- high precision
- genomic data
- gene ontology
- systems biology
- molecular biology
- ppi networks
- saccharomyces cerevisiae
- drug discovery
- protein interaction data
- network analysis
- predicting protein
- protein function
- data analysis
- computational approaches
- knowledge discovery
- genome wide
- biological networks
- protein interaction networks
- machine learning
- fine grained
- microarray data
- computational biology
- databases