From Hub Proteins to Hub Modules: The Relationship Between Essentiality and Centrality in the Yeast Interactome at Different Scales of Organization.
Jimin SongMona SinghPublished in: PLoS Comput. Biol. (2013)
Keyphrases
- protein protein interactions
- functional modules
- protein interaction
- network analysis
- protein interaction networks
- essential proteins
- high throughput
- protein complexes
- protein function
- computational methods
- protein protein
- protein interaction data
- gene ontology
- saccharomyces cerevisiae
- predicting protein
- biological processes
- biological networks
- ppi networks
- high precision
- biomedical literature
- drug design
- centrality measures
- systems biology
- protein protein interaction networks
- biological data
- network topology
- genomic data
- structural properties
- information systems
- wet lab
- regulatory networks
- cell cycle
- computational tools
- microarray
- social network analysis
- knowledge management
- text mining
- computational approaches
- protein function prediction
- budding yeast
- data sets