New Algorithm for Analysis of Off-target Effects in siRNA Screens.
Karol KozakSandra KaestnerThomas WildAndreas VonderheitBenjamin MisselwitzUlrike KutayGabor CsucsPublished in: BIOINFORMATICS (2013)
Keyphrases
- optimal solution
- preprocessing
- detection algorithm
- learning algorithm
- objective function
- search space
- expectation maximization
- dynamic programming
- particle swarm optimization
- high accuracy
- worst case
- computational cost
- theoretical analysis
- k means
- data analysis
- improved algorithm
- optimization algorithm
- selection algorithm
- single pass
- experimental evaluation
- np hard
- computational complexity
- probabilistic model
- cost function
- classification algorithm
- memory requirements
- convergence rate
- significant improvement
- estimation algorithm
- data mining