Comprehensive Structural and Functional Characterization of the Human Kinome by Protein Structure Modeling and Ligand Virtual Screening.
Michal BrylinskiJeffrey SkolnickPublished in: J. Chem. Inf. Model. (2010)
Keyphrases
- protein structure
- virtual screening
- drug discovery
- protein structural
- protein sequences
- similarity searching
- experimentally determined
- secondary structure
- protein structure prediction
- protein tertiary structure
- high throughput
- protein protein
- molecular biology
- binding sites
- protein backbone
- chemical compounds
- contact map
- nuclear magnetic resonance
- scoring function
- machine learning