Choosing negative examples for the prediction of protein-protein interactions.
Asa Ben-HurWilliam Stafford NoblePublished in: BMC Bioinform. (2006)
Keyphrases
- protein protein interactions
- negative examples
- protein interaction
- positive examples
- wet lab
- computational methods
- high throughput
- concept learning
- binary classification
- prediction accuracy
- training data
- network topology
- biological data
- high precision
- training examples
- background knowledge
- machine learning
- small number
- information extraction
- data sources
- decision trees
- learning algorithm