Inherent limitations of probabilistic models for protein-DNA binding specificity.
Shuxiang RuanGary D. StormoPublished in: PLoS Comput. Biol. (2017)
Keyphrases
- dna binding
- probabilistic model
- binding sites
- genome wide
- graphical models
- transcription factors
- gene expression
- bayesian networks
- bayesian inference
- high throughput
- dna sequences
- co occurrence
- text mining
- protein families
- sequence similarity
- highly similar
- cis regulatory
- motif discovery
- protein interaction
- component analysis
- microarray
- information extraction
- pairwise