Interaction Model Based on Local Protein Substructures Generalizes to the Entire Structural Enzyme-Ligand Space.
Helena StrömbergssonPawel DanilukAndriy KryshtafovychKrzysztof FidelisJarl E. S. WikbergGerard J. KleywegtTorgeir R. HvidstenPublished in: J. Chem. Inf. Model. (2008)
Keyphrases
- drug discovery
- amino acids
- drug design
- predicting protein
- protein interaction
- search space
- virtual screening
- space time
- data structure
- low dimensional
- protein protein
- protein sequences
- structural similarities
- protein folding
- protein protein interactions
- protein families
- physical space
- early stage
- sequence similarity
- high precision
- human computer interaction
- high dimensional