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Hierarchical Modeling of Activation Mechanisms in the ABL and EGFR Kinase Domains: Thermodynamic and Mechanistic Catalysts of Kinase Activation by Cancer Mutations.

Anshuman DixitGennady Verkhivker
Published in: PLoS Comput. Biol. (2009)
Keyphrases
  • information processing
  • real world
  • biological data
  • sequence alignment
  • application domains
  • hierarchical structure
  • modeling method
  • cancer diagnosis
  • activation patterns