Computational modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-kappaB signaling-induced gene expression responses in inflammation.
Shih Chi PengDavid Shan-Hill WongKai Che TungYan Yu ChenChun Cheih ChaoChien Hua PengYung-Jen ChuangChuan Yi TangPublished in: BMC Bioinform. (2010)
Keyphrases
- reverse engineering
- gene expression
- computational modeling
- genetic regulatory networks
- gene regulation
- gene regulatory networks
- microarray
- gene networks
- gene expression data
- genomic data
- dna binding
- software engineering
- high throughput
- microarray data
- regulatory networks
- biological networks
- transcription factors
- systems engineering
- network model
- computational model
- gene expression patterns
- object oriented
- biological processes
- gene expression profiles
- link prediction
- transcriptional regulation
- regulatory elements
- gene selection
- protein interaction networks
- databases
- industrial applications
- cognitive science
- complex networks
- data model
- data mining
- systems biology
- genomic sequences
- artificial intelligence
- machine learning