Replacement of Protein Binding-Site Waters Contributes to Favorable Halogen Bond Interactions.
Yuanxun WangQiuyu FuYu ZhouYunfei DuNiu HuangPublished in: J. Chem. Inf. Model. (2019)
Keyphrases
- protein protein
- binding sites
- protein interaction
- dna binding
- protein protein interactions
- virtual screening
- computational methods
- protein sequences
- gene expression
- predicting protein
- transcription factors
- interaction networks
- dna sequences
- sequence data
- sequence alignment
- high throughput
- protein structure
- protein complexes
- protein function
- regulatory elements
- transcription factor binding sites
- statistical significance
- biomedical literature
- biological processes
- motif discovery
- drug design
- molecular biology
- amino acid sequences
- biological data
- functional modules
- regulatory networks
- biological systems
- microarray
- genome wide
- computational approaches
- gene expression data
- cis regulatory