PROFALIGN Algorithm Identifies the Regions Containing Folding Determinants by Scoring Pairs of Hydrophobic Profiles of Remotely Related Proteins.
Olga TcheremenskaiaAlessandro GiulianiMaurizio TomasiPublished in: J. Comput. Biol. (2008)
Keyphrases
- np hard
- preprocessing
- cost function
- dynamic programming
- computational cost
- amino acids
- objective function
- optimal solution
- pairwise
- search space
- protein folding
- neural network
- protein structure
- detection algorithm
- optimization algorithm
- segmentation algorithm
- significant improvement
- learning algorithm
- worst case
- decision trees