Estimating Genome-Wide Copy Number Using Allele Specific Mixture Models.
Wenyi WangBenilton S. CarvalhoNate MillerJonathan PevsnerAravinda ChakravartiRafael A. IrizarryPublished in: RECOMB (2007)
Keyphrases
- mixture model
- genome wide
- high throughput
- dna copy number
- probabilistic model
- copy number
- generative model
- maximum likelihood
- single nucleotide polymorphisms
- em algorithm
- unsupervised learning
- model selection
- language model
- expectation maximization
- human genome
- data sets
- noise level
- data mining techniques
- machine learning