Motions of Allosteric and Orthosteric Ligand-Binding Sites in Proteins are Highly Correlated.
Xiaomin MaHu MengLuhua LaiPublished in: J. Chem. Inf. Model. (2016)
Keyphrases
- highly correlated
- binding sites
- protein protein
- dna binding
- transcription factors
- dna sequences
- protein protein interactions
- statistically significant
- statistical significance
- sequence data
- gene expression
- protein function
- average precision
- computational methods
- biological processes
- protein interaction
- high dimensionality
- protein sequences
- protein families
- high throughput
- cis regulatory
- protein complexes
- interaction networks
- transcription factor binding sites
- protein structure
- protein interaction networks
- drug design
- predicting protein
- microarray
- systems biology
- evaluation metrics
- retrieval systems
- amino acid sequences
- search engine
- machine learning
- data sets