MAPE-PPI: Towards Effective and Efficient Protein-Protein Interaction Prediction via Microenvironment-Aware Protein Embedding.
Lirong WuYijun TianYufei HuangSiyuan LiHaitao LinNitesh V. ChawlaStan Z. LiPublished in: ICLR (2024)
Keyphrases
- protein protein interactions
- protein interaction
- predicting protein
- drug design
- interacting proteins
- computational methods
- high throughput
- wet lab
- protein complexes
- biological processes
- protein interaction data
- predicting protein protein interactions
- protein function
- high precision
- protein protein
- network topology
- gene ontology
- systems biology
- ppi networks
- functional modules
- protein function prediction
- biomedical literature
- biological networks
- genomic data
- essential proteins
- biological data
- cellular processes
- network analysis
- multiple sequence alignments
- protein interaction networks
- biological knowledge
- experimentally determined
- saccharomyces cerevisiae
- structural properties
- computational approaches
- regulatory networks
- gene expression