False positive reduction in protein-protein interaction predictions using gene ontology annotations.
Mahmood A. MahdaviYen-Han LinPublished in: BMC Bioinform. (2007)
Keyphrases
- gene ontology
- false positives
- protein protein interactions
- microarray
- computational methods
- high throughput
- biological processes
- network topology
- high precision
- genomic data
- biological networks
- protein function
- biomedical literature
- protein interaction
- functional modules
- semantic similarity
- network analysis
- protein complexes
- information theoretic
- computational approaches
- biological data
- systems biology
- gene sets
- gene expression data
- saccharomyces cerevisiae
- protein interaction data
- structural properties
- gene expression
- signaling pathways