Biological Random Walks: multi-omics integration for disease gene prioritization.
Michele GentiliLeonardo MartiniMarialuisa SponzielloLuca BecchettiPublished in: Bioinform. (2022)
Keyphrases
- random walk
- molecular level
- gene function
- biological entities
- gene sets
- dna microarray
- protein protein interaction networks
- biological knowledge
- regulatory networks
- biologically meaningful
- directed graph
- gene expression analysis
- biological processes
- markov chain
- related genes
- microarray expression data
- gene expression
- single nucleotide polymorphisms
- microarray
- transition probabilities
- gene regulatory networks
- biological systems
- molecular biology
- disease genes
- biomedical literature
- candidate genes
- stationary distribution
- gene ontology
- biological data
- signaling pathways
- link prediction
- interaction networks
- gene expression patterns
- genome wide
- high throughput
- microarray data
- spectral methods
- gene expression data
- transition probability matrix
- markov random walk
- gene gene
- flow graph
- complex diseases
- computational approaches
- high dimensional
- web graph
- machine learning