Topology aware functional similarity of protein interaction networks based on gene ontology.
Fei LiXiuliang CuiDafei XieXiaochen BoShengqi WangPublished in: EMBC (2011)
Keyphrases
- gene products
- gene ontology
- protein interaction networks
- protein protein interactions
- protein interaction
- protein complexes
- functional modules
- protein function
- biological networks
- interaction networks
- semantic similarity
- gene expression
- microarray
- protein interaction data
- computational methods
- high throughput
- protein function prediction
- network topology
- complex networks
- biological processes
- biological data
- biological systems
- similarity measure
- network analysis
- computational approaches
- high precision
- biomedical literature
- community detection
- information theoretic
- co occurrence
- gene regulatory networks
- systems biology
- machine learning
- graph mining
- information flow
- link prediction
- wordnet