Genome Landscapes of Disease: Strategies to Predict the Phenotypic Consequences of Human Germline and Somatic Variation.
Rachel KarchinRuth NussinovPublished in: PLoS Comput. Biol. (2016)
Keyphrases
- genotype phenotype
- copy number
- single nucleotide polymorphisms
- genetic variation
- human genome
- gene expression programming
- genomic data
- complex diseases
- human subjects
- genome wide
- computational approaches
- evolutionary history
- human operators
- evolutionary algorithm
- optimal strategy
- sequence data
- fitness landscape
- human interaction
- human users
- dna sequences