Drug response prediction by ensemble learning and drug-induced gene expression signatures.
Mehmet TanOzan Firat ÖzgülBatuhan BardakIsiksu EksiogluSuna SabuncuogluPublished in: CoRR (2018)
Keyphrases
- gene expression
- ensemble learning
- microarray
- gene expression data
- ensemble methods
- drug design
- prediction accuracy
- generalization ability
- gene expression levels
- microarray data
- gene expression patterns
- protein interaction
- drug discovery
- binding sites
- unlabeled data
- machine learning
- support vector machine svm
- random forest
- concept drift
- feature selection
- high dimensionality
- base classifiers
- information extraction
- data sets