Characterization of the Effects of TF Binding Site Variations on Gene Expression Towards Predicting the Functional Outcomes of Regulatory SNPs.
Michal LapidotYitzhak PilpelPublished in: Systems Biology and Regulatory Genomics (2005)
Keyphrases
- transcription factors
- gene expression
- binding sites
- genome wide
- genomic data
- microarray
- dna sequences
- gene regulation
- post transcriptional
- dna binding
- high throughput
- regulatory elements
- gene expression levels
- regulatory networks
- gene expression data
- biological processes
- microarray data
- motif discovery
- cis regulatory
- sequence data
- human genome
- component analysis
- gene expression patterns
- systems biology
- saccharomyces cerevisiae
- protein families
- transcription factor binding sites
- gene expression profiles
- protein interaction
- transcriptional regulation
- co occurrence
- gene sets
- computational biology
- single nucleotide polymorphisms
- statistical significance
- machine learning