Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug.
Hee LeeTaejeong BaeJi-Hyun LeeDae KimYoung OhYeongjun JangJi-Tea KimJong Jun LeeAlessio InnocentiClaudiu T. SupuranLuonan ChenKyoohyoung RhoSunghoon KimPublished in: BMC Syst. Biol. (2012)
Keyphrases
- drug discovery
- virtual screening
- drug design
- chemical compounds
- physico chemical
- systems biology
- early stage
- network structure
- network model
- protein protein interaction networks
- network traffic
- complex networks
- interaction networks
- mass spectrometry data
- decision making
- protein structure
- biological systems
- neural network
- protein interaction networks
- peer to peer
- subcellular localization