Nuclear factor-I and activator protein-2 bind in a mutually exclusive way to overlapping promoter sequences and trans-activate the human growth hormone gene.
S. J. CourtoisDaniel A. LafontaineF. P. LemaigreS. M. DurviauxG. G. RousseauPublished in: Nucleic Acids Res. (1990)
Keyphrases
- sequence alignment
- transcription factor binding sites
- genomic sequences
- binding sites
- protein interaction
- cis regulatory
- escherichia coli
- nucleotide sequences
- protein sequences
- genome sequences
- gene expression
- regulatory elements
- multiple sequence alignment
- sequence analysis
- computational biology
- dna sequences
- transcriptional regulation
- sequence data
- protein protein interaction networks
- gene prediction
- regulatory networks
- protein protein interactions
- physico chemical
- biological entities
- protein structure
- microarray
- gene expression data
- physicochemical properties
- microarray data
- saccharomyces cerevisiae
- statistical significance
- protein families
- biological data
- genomic data
- transcription factors