In Silico Identification and Biological Evaluation of Novel Selective Serum/Glucocorticoid-Inducible Kinase 1 Inhibitors Based on the Pyrazolo-Pyrimidine Scaffold.
Francesco OrtusoRosario AmatoAnna ArteseLucia D'antonaGiosuè CostaCristina TalaricoFrancesco GigliottiCataldo BiancoFrancesco TrapassoSilvia SchenoneFrancesca MusumeciLorenzo BottaNicola PerrottiStefano AlcaroPublished in: J. Chem. Inf. Model. (2014)
Keyphrases
- biological data
- high throughput
- protein protein interactions
- molecular biology
- biological processes
- data integration
- data analysis
- systems biology
- life sciences
- statistical methods
- microarray data
- evaluation method
- evaluation model
- evaluation criteria
- biological networks
- evaluation methods
- databases
- reverse engineering
- high dimensional
- machine learning