Boosting Prediction Performance of Protein-Protein Interaction Hot Spots by Using Structural Neighborhood Properties - (Extended Abstract).
Lei DengJihong GuanXiaoming WeiYuan YiShuigeng ZhouPublished in: RECOMB (2013)
Keyphrases
- extended abstract
- hot spots
- protein protein interactions
- experimentally determined
- protein interaction
- predicting protein
- wet lab
- drug design
- structural properties
- high throughput
- computational methods
- gene ontology
- protein function prediction
- network topology
- high precision
- predicting protein protein interactions
- protein complexes
- protein function
- biological data
- multiple sequence alignments
- computational approaches
- biological processes
- network analysis
- genomic data
- functional modules
- biological networks
- protein interaction networks
- gene expression
- feature selection
- databases