Discovering Missing Edges in Drug-Protein Networks: Repurposing Drugs for SARS-CoV-2.
Fatemeh ZareMehrjardiAthar OmidiCristina SciortinoRyan E. R. ReidRyan LukemanJames Alexander HughesOthman SoufanPublished in: CIBCB (2021)
Keyphrases
- drug design
- drug discovery
- virtual screening
- chemical compounds
- protein structure prediction
- pharmaceutical industry
- physico chemical
- subcellular localization
- missing links
- similarity searching
- biological systems
- protein protein interactions
- early stage
- biological networks
- protein interaction networks
- edge detector
- high throughput
- complex networks
- protein protein interaction networks
- directed edges
- scoring function
- mass spectrometry
- social networks
- systems biology
- public health
- network model
- amino acids
- weighted graph
- microarray
- missing data