A statistical method for the detection of variants from next-generation resequencing of DNA pools.
Vikas BansalPublished in: Bioinform. (2010)
Keyphrases
- detection method
- pairwise
- similarity measure
- clustering method
- significant improvement
- segmentation method
- objective function
- dynamic programming
- support vector machine svm
- computational cost
- optimization method
- high precision
- detection algorithm
- computationally efficient
- high accuracy
- neural network
- experimental evaluation
- cost function
- prior knowledge
- preprocessing
- statistical information
- probabilistic model
- statistical analysis
- feature extraction