Rational Discovery of GSK3-Beta Modulators Aided by Protein Pocket Prediction and High-Throughput Molecular Docking.
Rafael DolezalMichaela MelikovaJakub MesicekKamil KucaPublished in: ICCCI (2) (2016)
Keyphrases
- high throughput
- protein protein interactions
- hiv protease
- mass spectrometry
- protein protein
- virtual screening
- drug design
- protein interaction
- microarray
- biological data
- genome wide
- systems biology
- protein function prediction
- mass spectrometry data
- interaction networks
- genomic data
- protein structure prediction
- predicting protein
- protein function
- drug discovery
- protein interaction data
- data acquisition
- functional modules
- proteomic data
- biomedical literature
- biological knowledge
- transcriptional regulation
- protein complexes
- regulatory networks
- biological networks
- protein interaction networks
- biological processes
- saccharomyces cerevisiae
- discovery process
- genome sequencing
- living cells
- computational methods
- gene ontology
- high speed
- ms ms
- coarse grained
- molecular biology
- computational approaches
- experimental conditions
- gene expression
- sequence analysis
- knowledge discovery