A block-based evolutionary optimization strategy to investigate gene-gene interactions in genetic association studies.
Joel FontanarosaYang DaiPublished in: BIBM Workshops (2010)
Keyphrases
- gene gene interactions
- genome wide
- optimization strategy
- grammatical evolution
- association studies
- high throughput
- complex diseases
- single nucleotide polymorphisms
- haplotype inference
- human genome
- optimization algorithm
- improved algorithm
- genetic programming
- decision trees
- linkage disequilibrium
- particle swarm
- genetic algorithm
- transcription factors
- microarray
- initial solution