Scalable Parameter Estimation for Genome-Scale Biochemical Reaction Networks.
Fabian FröhlichBarbara KaltenbacherFabian J. TheisJan HasenauerPublished in: PLoS Comput. Biol. (2017)
Keyphrases
- parameter estimation
- genome scale
- maximum likelihood
- markov random field
- model selection
- least squares
- statistical models
- systems biology
- em algorithm
- parameter estimation algorithm
- experimental data
- approximate inference
- sequence similarity
- network analysis
- social networks
- structure learning
- gene regulatory networks
- expectation maximization
- network structure
- high throughput
- metabolic pathways
- computer vision
- community detection
- network model
- complex networks
- higher order
- feature selection
- data mining