MAPE-PPI: Towards Effective and Efficient Protein-Protein Interaction Prediction via Microenvironment-Aware Protein Embedding.
Lirong WuYijun TianYufei HuangSiyuan LiHaitao LinNitesh V. ChawlaStan Z. LiPublished in: CoRR (2024)
Keyphrases
- protein protein interactions
- protein interaction
- predicting protein
- drug design
- interacting proteins
- protein complexes
- wet lab
- protein protein
- computational methods
- protein interaction data
- network topology
- high throughput
- protein function
- experimentally determined
- predicting protein protein interactions
- biological processes
- gene ontology
- ppi networks
- genomic data
- functional modules
- protein interaction networks
- protein function prediction
- biomedical literature
- high precision
- cellular processes
- essential proteins
- biological data
- computational approaches
- systems biology
- saccharomyces cerevisiae
- biological networks
- multiple sequence alignments
- structural properties
- regulatory networks
- gene expression
- secondary structure
- graph theory
- biological knowledge
- microarray