Identifying mutual exclusivity across cancer genomes: computational approaches to discover genetic interaction and reveal tumor vulnerability.
Yulan DengShangyi LuoChunyu DengTao LuoWenkang YinHongyi ZhangYong ZhangXinxin ZhangYujia LanYanyan PingYun XiaoXia LiPublished in: Briefings Bioinform. (2019)
Keyphrases
- computational approaches
- copy number
- breast cancer
- single nucleotide polymorphisms
- computational methods
- human genome
- cancer diagnosis
- normal tissue
- tissue samples
- cell lines
- cancer cells
- protein interaction
- protein protein interactions
- computational tools
- protein complexes
- protein sequences
- lung cancer
- gene selection
- protein structure
- machine learning
- radiation dose
- databases
- secondary structure
- data mining