A drug target slim: using gene ontology and gene ontology annotations to navigate protein-ligand target space in ChEMBL.
Prudence Mutowo-MeullenetA. Patrícia BentoNathan DedmanAnna GaultonAnne HerseyJane LomaxJohn P. OveringtonPublished in: J. Biomed. Semant. (2016)
Keyphrases
- gene ontology
- protein protein interactions
- protein function
- protein protein
- microarray
- protein interaction
- high throughput
- protein interaction data
- gene products
- computational methods
- genomic data
- semantic similarity
- biological networks
- information theoretic
- microarray expression data
- interaction networks
- protein function prediction
- signaling pathways
- virtual screening
- high precision
- gene networks
- biomedical literature
- structural properties
- biological data
- drug discovery
- gene sets
- biological processes
- gene expression
- network topology
- protein complexes
- computational approaches
- microarray data