Single nucleotide polymorphisms affect RNA-protein interactions at a distance through modulation of RNA secondary structures.
Elan ShatoffRalf BundschuhPublished in: PLoS Comput. Biol. (2020)
Keyphrases
- rna secondary structures
- protein interaction
- secondary structure
- single nucleotide polymorphisms
- protein protein interactions
- computational approaches
- computational methods
- genome wide
- edit distance
- high throughput
- rna sequences
- stochastic context free grammars
- distance measure
- biological data
- genomic data
- dna sequences
- gene expression
- biological processes
- systems biology
- biomedical literature
- bayesian networks
- human genome
- biological systems
- protein sequences
- computational tools
- binding sites
- protein structure
- machine learning