Discovery of Novel Cathepsin S Inhibitors by Pharmacophore-Based Virtual High-Throughput Screening.
Patrick MarktCaroline McGoohanBrian WalkerJohannes KirchmairClemens FeldmannGabriella De MartinoGudrun M. SpitzerSimona DistintoDaniela SchusterGerhard WolberChristian LaggnerThierry LangerPublished in: J. Chem. Inf. Model. (2008)
Keyphrases
- high throughput
- drug discovery
- systems biology
- protein protein interactions
- microarray
- genome wide
- biological data
- mass spectrometry
- discovery process
- virtual screening
- genomic data
- data mining
- data acquisition
- knowledge discovery
- low latency
- early stage
- machine learning
- dna sequencing
- experimental conditions
- biological processes
- image analysis
- biological knowledge
- data sets
- mass spectrometry data
- proteomic data
- analysis of gene expression