Structure-based design of ligands for protein basic domains: Application to the HIV-1 Tat protein.
Anton V. FilikovThomas L. JamesPublished in: J. Comput. Aided Mol. Des. (1998)
Keyphrases
- contact map
- molecular structures
- drug design
- protein sequences
- molecular dynamics
- protein structure
- drug discovery
- physicochemical properties
- protein function
- protein structure prediction
- virtual screening
- structural motifs
- sequence alignment
- amino acids
- protein folding
- protein interaction data
- mass spectrometry data
- amino acid sequences
- predicting protein
- protein interaction networks
- sequence analysis
- data mining
- multiple sequence alignment
- mass spectrometry
- protein interaction
- design space
- protein protein interactions
- high throughput