Pathogenicity Prediction of Single Amino Acid Variants With Machine Learning Model Based on Protein Structural Energies.
Tzu-Hsuan WuPeng-Chan LinHsin-Hung ChouMeng-Ru ShenSun-Yuan HsiehPublished in: IEEE ACM Trans. Comput. Biol. Bioinform. (2023)
Keyphrases
- protein sequences
- amino acids
- protein structural
- machine learning
- protein structure
- psi blast
- computational biology
- protein classification
- protein structure prediction
- prediction accuracy
- secondary structure
- protein secondary structure prediction
- physico chemical
- experimentally determined
- contact maps
- tertiary structure
- molecular biology
- contact map
- protein function
- physicochemical properties
- feature selection
- sequence analysis
- data analysis
- sequence alignment
- knowledge discovery
- information extraction