Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments.
Michael L. SierkMichael E. SmootEllen J. BassWilliam R. PearsonPublished in: BMC Bioinform. (2010)
Keyphrases
- sequence alignment
- protein sequences
- pairwise
- multiple sequence alignments
- amino acids
- multiple alignment
- computational biology
- protein structure
- protein classification
- high accuracy
- multiple sequence alignment
- protein structure prediction
- amino acid sequences
- dynamic programming
- coarse grained
- secondary structure
- highly accurate
- protein secondary structure
- protein structural
- prediction accuracy
- protein function
- binding sites
- protein folding
- comparative genomics
- structural motifs
- similarity measure
- molecular biology