Predicting synthetic lethal interactions using conserved patterns in protein interaction networks.
Graeme Benstead-HumeXiangrong ChenSuzanna R. HopkinsKaren A. LaneJessica A. DownsFrances M. G. PearlPublished in: PLoS Comput. Biol. (2019)
Keyphrases
- protein interaction networks
- protein interaction
- functional modules
- protein complexes
- biological data mining
- protein protein interactions
- protein function
- graph theoretic
- computational methods
- biological networks
- binding sites
- frequent patterns
- minimum spanning tree
- pattern discovery
- pattern mining
- complex networks
- sequential patterns
- gene expression