Joint eQTL mapping and inference of gene regulatory network improves power of detecting both cis- and trans-eQTLs.
Xin ZhouXiaodong CaiPublished in: Bioinform. (2021)
Keyphrases
- gene regulatory networks
- gene expression
- gene expression data
- undirected graphical models
- dynamic bayesian networks
- linkage disequilibrium
- bayesian inference
- microarray
- network model
- bayesian networks
- structure learning
- probabilistic inference
- reverse engineering
- metropolis hastings algorithm
- graphical models
- systems biology
- exact inference
- conditional random fields
- approximate inference
- biological data
- binding sites
- particle filtering
- prior information
- high throughput
- high speed
- probabilistic model
- neural network
- data sets