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A Combined Ligand- and Structure-Based Virtual Screening To Identify Novel NaV1.2 Blockers: In Vitro Patch Clamp Validation and In Vivo Anticonvulsant Activity.

Manuel A. LlanosNicolas EnriqueVega Esteban-LópezSebastian Scioli-MontotoDavid Sánchez-BenitoMaría E. RuizVeronica MilesiDolores E. LópezAlan TaleviPedro MartínLuciana Gavernet
Published in: J. Chem. Inf. Model. (2023)
Keyphrases
  • virtual screening
  • drug discovery
  • similarity searching
  • chemical structures
  • data mining
  • high throughput
  • databases
  • metadata
  • multi dimensional
  • similarity search