SubClonal Hierarchy Inference from Somatic Mutations: Automatic Reconstruction of Cancer Evolutionary Trees from Multi-region Next Generation Sequencing.
Noushin NiknafsVioleta Beleva GuthrieDaniel Q. NaimanRachel KarchinPublished in: PLoS Comput. Biol. (2015)
Keyphrases
- evolutionary process
- genetic algorithm
- tree structure
- bayesian networks
- evolutionary computation
- breast cancer
- phylogenetic trees
- higher level
- belief networks
- probabilistic inference
- lower level
- gene selection
- maximum parsimony
- data sets
- inference process
- early detection
- dynamic bayesian networks
- bayesian inference
- region of interest
- neural network