Estimating the rate of molecular evolution: incorporating non-contemporaneous sequences into maximum likelihood phylogenies.

Published in: Bioinform. (2000)

Keyphrases

maximum likelihood
phylogenetic trees
maximum parsimony
em algorithm
parameter estimation
sequence analysis
expectation maximization
maximum likelihood estimates
machine learning
three dimensional
hidden markov models
gaussian distribution
rigid body
likelihood function
maximum a posteriori
temporal behavior