A mixture model for expression deconvolution from RNA-seq in heterogeneous tissues.
Yi LiXiaohui XiePublished in: BMC Bioinform. (2013)
Keyphrases
- mixture model
- rna seq
- gaussian mixture model
- density estimation
- generative model
- probabilistic model
- em algorithm
- high throughput
- maximum likelihood
- expectation maximization
- model selection
- mixture modeling
- unsupervised learning
- language model
- denoising
- probabilistic mixture model
- gaussian mixture
- gene expression
- alternative splicing
- medical images
- high dimensional
- bayesian networks