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Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference.

Chunhui CaiGregory F. CooperKevin N. LuXiaojun MaShuping XuZhenlong ZhaoXueer ChenYifan XueAdrian V. LeeNathan ClarkVicky ChenSongjian LuLujia ChenLiyue YuHarry HochheiserXia JiangQ. Jane WangXinghua Lu
Published in: PLoS Comput. Biol. (2019)
Keyphrases
  • causal inference
  • additive noise
  • observational data
  • brain tumors
  • normal tissue
  • experimental data
  • discovery process
  • knowledge base
  • causal models