Identifying disease-specific genes based on their topological significance in protein networks.
Zoltán DezsöYuri NikolskyTatiana NikolskayaJeremy MillerDavid CherbaCraig WebbAndrej BugrimPublished in: BMC Syst. Biol. (2009)
Keyphrases
- protein protein interaction networks
- signaling pathways
- gene regulatory networks
- biological entities
- disease genes
- gene expression
- regulatory networks
- saccharomyces cerevisiae
- biological knowledge
- candidate genes
- gene gene interactions
- interaction networks
- biological networks
- gene networks
- complex diseases
- gene expression data
- functional modules
- cellular processes
- differentially expressed genes
- complex networks
- social networks
- amino acids
- biological processes
- biomedical literature
- gene function
- microarray data
- protein interaction data
- drosophila melanogaster
- gene selection