Binding Profiles of Chromatin-Modifying Proteins Are Predictive for Transcriptional Activity and Promoter-Proximal Pausing.
Thomas SakoparnigTobias KockmannRenato ParoChristian BeiselNiko BeerenwinkelPublished in: J. Comput. Biol. (2012)
Keyphrases
- transcription factors
- dna binding
- cis regulatory
- binding sites
- genome wide
- gene regulation
- gene expression
- microarray
- component analysis
- dna sequences
- regulatory networks
- computational biology
- transcription factor binding sites
- biological processes
- high throughput
- saccharomyces cerevisiae
- systems biology
- co occurrence
- transcriptional regulation
- highly correlated
- microarray data
- motif discovery
- protein interaction
- cell cycle
- cellular processes
- user profiles
- biomedical literature
- living cells
- transcriptional regulatory
- biological sequences
- molecular biology
- sequence data
- biological systems
- gene sets
- functional modules
- human genome
- statistical significance
- gene selection
- protein sequences