MethylCRF, an Algorithm for Estimating Absolute Methylation Levels at Single CpG Resolution from Methylation Enrichment and Restriction Enzyme Sequencing Methods.
Michael StevensJeffrey B. ChengMingchao XieJoseph F. CostelloTing WangPublished in: RECOMB (2013)
Keyphrases
- synthetic and real datasets
- significant improvement
- dynamic programming
- computational cost
- detection algorithm
- preprocessing
- matching algorithm
- learning algorithm
- computational complexity
- np hard
- synthetic and real images
- exhaustive search
- iterative algorithms
- heuristic methods
- convergence rate
- noisy data
- synthetic datasets
- segmentation algorithm
- theoretical guarantees
- computationally demanding
- test images
- interpolation method
- probabilistic model
- objective function