Generating novel molecule for target protein (SARS-CoV-2) using drug-target interaction based on graph neural network.
Amit RanjanShivansh ShuklaDeepanjan DattaRajiv MisraPublished in: Netw. Model. Anal. Health Informatics Bioinform. (2022)
Keyphrases
- neural network
- protein interaction
- drug discovery
- protein interaction networks
- graph structure
- protein protein interactions
- protein sequences
- chemical compounds
- weighted graph
- graph representation
- random walk
- bipartite graph
- graph theory
- structured data
- fuzzy logic
- pattern recognition
- protein interaction data
- amino acids
- gene expression
- back propagation
- human computer interaction
- bp neural network
- graph matching
- protein structure
- artificial neural networks
- graph model
- neural network is trained
- neural network model
- directed graph
- user interaction
- protein function
- severe acute respiratory syndrome
- subcellular localization
- protein function prediction
- functional modules
- graph kernels
- gene ontology
- graph theoretic
- public health
- graph databases
- graph mining
- network model
- feed forward