MOPED: Method for optimizing physical energy parameters using decoys.
Chaok SeokJ. Ben RosenJohn D. ChoderaKen A. DillPublished in: J. Comput. Chem. (2003)
Keyphrases
- high accuracy
- computational cost
- detection method
- fine tuning
- experimental evaluation
- synthetic data
- minimum energy
- control parameters
- maximum likelihood estimation
- sensitivity analysis
- high precision
- clustering method
- input data
- parameter selection
- parameter settings
- segmentation algorithm
- maximum likelihood
- data sets
- least squares
- classification accuracy
- probabilistic model
- cost function
- significant improvement
- prior knowledge
- computational complexity
- multiscale
- learning algorithm