Designing Focused Chemical Libraries Enriched in Protein-Protein Interaction Inhibitors using Machine-Learning Methods.
Christelle ReynèsHélène HostAnne-Claude CamprouxGuillaume LacondeFlorence LerouxAnne MazarsBenoit DeprezRobin FahraeusBruno O. VilloutreixOlivier SperandioPublished in: PLoS Comput. Biol. (2010)
Keyphrases
- protein protein interactions
- wet lab
- high throughput
- computational methods
- protein interaction
- network topology
- predicting protein protein interactions
- biomedical literature
- gene ontology
- biological processes
- biological data
- structural properties
- protein complexes
- functional modules
- genomic data
- systems biology
- predicting protein
- high precision
- ppi networks
- digital libraries
- network analysis
- protein interaction networks
- computational approaches
- biological networks
- protein protein interaction networks
- chemical compounds
- wireless networks
- drug discovery
- regulatory networks
- protein interaction data